Performance of Creatinine and Cystatin C-Based Equations to to Estimate Kidney Function in Renal Transplant Recipients
نویسندگان
چکیده
Background: Numerous equations are applied in order to estimate the glomerular filtration rate (GFR). Objectives: This study aimed spot optimal equation that accurately estimates GFR and, therefore, chronic kidney disease (CKD) stage renal transplant patients. Methods: cross-sectional was conducted on 58 Their venous blood samples were obtained for serum creatinine and cystatin C determination used calculate estimated (eGFR). The average contrast of each calculated using Bland-Altman method. correlation, bias, imprecision, 10% 30% accuracy compared between eGFR creatinine. Concordance both CKD staging assessed. classification patients also investigated. Results: plots bias demonstrated by abbreviated modification diet (Ab-MDRD) most accurate with epidemiology collaboration (CKD-EPI) C, followed CKD-EPI With reference imprecision approximately similar Ab-MDRD, is still better than Cockcroft-gault (CG) formula. They showed good accuracy. Finally, our finding suggested Ab-MDRD might be best-performing stages a cutoff 60 mL/min/1.73 m2. Conclusions: Due high cost potential delay measuring it would much more appropriate measure Ab-MDRD; after that, as an alternative approach facilitate rapid clinical decision
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Determining an accurate method to estimate GFR in renal transplant recipients with stable serum creatinine levels
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متن کاملCystatin C and renal function in pediatric kidney transplant recipients.
In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation be...
متن کاملCystatin C and renal function in pediatric renal transplant recipients
In clinical practice, the glomerular filtration rate (GFR) is often determined with serum creatinine. However, studies have shown cystatin C to be a better parameter for the diagnosis of impaired renal function. We compared GFR estimated by plasma cystatin C with GFR estimated by serum creatinine in a sample of 50 pediatric renal transplant recipients and 24 healthy children. The correlation be...
متن کاملRe: estimation of glomerular filtration rate with creatinine-based versus cystatin C-based equations in kidney transplant recipients.
EDITOR, I read the recent publication by Savaj and colleagues in the Iranian Journal of Kidney Disease with great interest.1 Savaj and colleagues reached to the conclusion that “MDRD [the modification of diet in renal disease] equation could provide a closer estimate of GFR [glomerular filtration rate] to the cystatin C-based equations than other creatinine-based GFR calculations in kidney tran...
متن کاملEstimation of glomerular filtration rate with creatinine-based versus cystatin C-based equations in kidney transplant recipients.
INTRODUCTION Serum cystatin C is more sensitive for glomerular filtration rate (GFR) measurement, but it is not available for clinical use in all laboratories. Regarding the importance of accurate estimation of GFR in kidney transplant recipients, we compared cystatin C-based equations with creatinine-based formulas to estimate GFR as precisely and simply as possible in kidney transplant recipi...
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ژورنال
عنوان ژورنال: Nephro-urology monthly
سال: 2023
ISSN: ['2251-7006', '2251-7014']
DOI: https://doi.org/10.5812/numonthly-129099